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Our squalene production line utilizes advanced molecular distillation and purification technology, featuring a fully continuous, automated, and enclosed design. It ensures high-purity squalene yield, low energy consumption, excellent product quality, and meets strict pharmaceutical and cosmetic-grade standards. Suitable for processing plant-based oils (olive, amaranth, rice bran) into high-value squalene, the line integrates intelligent control, multi-stage purification, and nitrogen protection systems to deliver stable and economical production.
1.Raw Material Pretreatment Section
Plant-based raw materials (olive oil deodorizer distillate, rice bran oil wax, amaranth seed oil) undergo thorough preparation:
Filtration: Removal of solid impurities through precision filtration systems
Dehydration: Moisture content control using vacuum drying technology
Standardization: Batch composition stabilization through blending and analysis
2. Extraction & Concentration Section
Molecular Distillation (Core Technology): Multi-stage short-path distillation separates squalene from other components under high vacuum (0.001-1 mbar) at controlled temperatures (150-250°C), achieving initial squalene concentration >70%
Solvent Extraction Option: Alternative method using selective solvents (hexane/acetone) with complete solvent recovery systems (>99.5% recovery rate)
3. Refining & Purification Section
Esterification/Saponification: Converts residual free fatty acids to easily removable esters or soaps
Decolorization: Activated carbon/clay treatment removes pigments and impurities
Secondary Molecular Distillation/Chromatography: Final purification stage achieving >90-98% purity levels
4. Post-Processing & Filling Section
Precision Filtration: 0.2-0.45 micron filtration for particle-free product
Deoxygenation/Nitrogen Blanketing: Continuous nitrogen protection maintaining O₂ <50ppm
Automated Filling: Light-protected packaging (amber glass/aluminum containers) in nitrogen atmosphere
High Purity Output
Advanced molecular distillation and secondary purification ensure pharmaceutical-grade squalene with purity >98%, meeting USP/EP standards for cosmetic and pharmaceutical applications.
Sustainable & Traceable
100% plant-based raw materials from certified sustainable sources, complete documentation from raw material to finished product ensuring full traceability and compliance with environmental regulations.
Oxidation Prevention System
Integrated nitrogen generation, purification, and blanketing systems maintain oxygen levels below 50ppm throughout production and packaging, significantly extending product shelf life.
Fully Automated & Validated
PLC-based control system with SCADA interface provides real-time monitoring of all critical parameters (temperature, pressure, vacuum, purity). System designed for easy validation following GMP guidelines.
Our squalene production line is optimized for processing various plant-based oil by-products into high-purity squalene, including Olive Oil Deodorizer Distillate (ODD), Amaranth Seed Oil, Rice Bran Oil Wax, Palm Fatty Acid Distillate (PFAD), Soybean Oil By-products etc. These renewable sources provide consistent quality squalene for cosmetics, nutraceuticals, and pharmaceutical industries.
The core separation unit features multi-stage short-path distillation with high vacuum capability (<0.001 mbar). Constructed with 316L stainless steel and equipped with internal condensers, the system achieves separation temperatures 150-250°C with minimal thermal degradation. Automated feed rate control and continuous scraping ensure optimal separation efficiency.
Used in the pretreatment and refining stages for solid-liquid separation. Features polypropylene plates with cake discharge automation, effectively removing solid impurities, activated carbon, and decolorizing agents. Designed with CIP cleaning system and safety interlocks for continuous operation in squalene purification processes.
Critical equipment for removing free fatty acids (FFA) during squalene purification. Utilizes counter-current steam stripping under vacuum conditions to reduce FFA content below 0.1%. Constructed with 316L stainless steel, equipped with structured packing for maximum contact efficiency and automatic temperature-pressure control systems.
Q.What purity levels can be achieved?
A: Our standard line produces >90% purity for cosmetic grade and >98% for pharmaceutical grade. Custom configurations can achieve >99.5% purity for specialty applications.
Q.What is the production capacity range?
A:Standard lines from 10TPD to 300TPD. Custom designs available for pilot-scale (1TPD) or large-scale (500TPD+) requirements.
Q.Is the process suitable for pharmaceutical applications?
A: Yes, the system is designed following GMP principles with full validation documentation. All contact surfaces are 316L stainless steel, and the enclosed design prevents contamination.
Q. How is oxidation prevented during production?
A:Integrated nitrogen systems maintain inert atmosphere from distillation through packaging. Oxygen sensors continuously monitor critical points with automatic nitrogen purge activation if levels exceed limits.
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